MARCKS protein is transcriptionally down-regulated in v-Src-transformed BALB/c 3T3 cells.
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چکیده
منابع مشابه
MARCKS protein is transcriptionally down-regulated in v-Src-transformed BALB/c 3T3 cells.
Activation of protein kinase C (PKC) by tumor-promoting phorbol esters leads to the phosphorylation of an 80-kilodalton PKC substrate (known as MARCKS) in murine fibroblasts. In BALB/c 3T3 cells stably transformed by v-Src, phorbol esters were unable to induce phosphorylation of MARCKS. Western blot analysis and in vitro kinase assays showed that both PKC protein levels and kinase activity were...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1992
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)48433-5